Abstract: Objective To investigate the clinical effect of damage control resuscitation（DCR） scheme combined with massive transfusion pattern (MTP) on acute traumatic coagulopathy. Methods Thirty-eight patients who had severe traumatic coagulopathy in ICU were randomly divided into treatment group (n=20) and control group（n=18）. The patients in treatment group adopted DCR combined with MTP, while control group adopted traditional method. The blood coagulat-ion function was analyzed after 12 h and 72 h by prothrombin time（PT）,international normalized ratio（INR）,acti-vated partial thromboplastin time（APTT）,fibrinogen（FIB）,and platelets. The total amount of RBC during 72 h,the days of hospital ICU stay,the corrected rate of shock,and the 30-day survival rate. Results Compared with the control group,the treatment group showed a quick recovery of blood coagulation function. The total amount of PRBC during 72 h,the days of ICU stay in the treatment group were less than those in control group,while the corrected rate of shock and the 30-day survival rate were higher than those of control group（P<0.05）. Conclusion DCR scheme, combined with MTP program,has a promising effect on blood coagulation improvement,hemostasis,and the survival rate increase of patients.

Key words: Coagulation management in earlier stage, Acute traumatic coagulopaty, Clinical outcome