Abstract: Objective To evaluate the potential use of OSTA in bone density assessment in the elderly patients with chronic obstructive pulmonary disease （COPD）. Methods Based on risk stratification of OSTA,a correlation analysis of 120 patients with respiratory diseases were performed,among them 60 cases were COPD. Results No significant difference of osteoporosis at high-risk was seen when compared with the control. The OSTA was positively associated with bone density,weights and IC but negatively correlated to age,height,and concentrations of PINP and CTX,IL-8,IL-13,and TGF-β1. Conclusion The chronic obstructive pulmonary disease is a high risk factor of osteoporosis in senior patients and the OSTA is simple and economic for primary screening of osteoporosis in these patients.

Key words: OSTA, Osteoporosis, Chronic obstructive pulmonary disease