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临床输血与检验 ›› 2019, Vol. 21 ›› Issue (1): 70-73.DOI: 10.3969/j.issn.1671-2587.2019.01.024

• 临床检验 • 上一篇    下一篇

婴儿川崎病的早期临床和血液学特点

张永远, 温晓红   

  1. 230061 安徽省合肥市第一人民集团医院,合肥市滨湖医院
  • 收稿日期:2018-08-27 出版日期:2019-02-20 发布日期:2019-01-28
  • 通讯作者: 温晓红,女,主任医师,主要从事儿内科工作,(E-mail)wenxiaohong@163.com。
  • 作者简介:张永远(1984-),男,主治医师,硕士,主要从事儿内科工作,(E-mail)272565632@qq.com。

Characteristics of Early Clinic and Hematology in Infants with Kawasaki Disease

ZHANG Yong-yuan, WEN Xiao-hong   

  1. Department of Pediatric,Binhu Hospital of Southern District,First Hospital of Hefei City,Hefei 230061
  • Received:2018-08-27 Online:2019-02-20 Published:2019-01-28

摘要: 目的 总结婴儿川崎病的早期临床表现和检验结果,利于早期诊断。方法 对21例婴儿川崎病患儿的病例资料进行回顾性分析,并与同期诊治的20例1岁以上川崎病患儿对比分析。结果 婴儿川崎病早期临床表现出现卡巴红斑,消化系统及神经系统症状增多,颈部淋巴结肿大较少,不完全川崎病发病率升高,差异有统计学意义(P<0.05)。在早期检验方面,PLT、CRP、ESR、ALB、CK-MB相比差异无统计学意义,WBC水平高,Hb水平低,肝损害及冠脉损害发生率升高,差异有统计学意义(P<0.05)。结论 婴儿川崎病中不完全川崎病及冠状动脉损害发生率高,除了观察川崎病的主要表现,还应注意观察卡巴红斑、消化系统及神经系统症状等,监测WBC、Hb、PLT、CRP、ESR、ALT,适时完善心脏超声检查,以利于对婴儿川崎病的早期诊断。

关键词: 婴儿, 川崎病, 临床表现, 血液学特点

Abstract: Objective we summarized early clinical characteristics of infants with Kawasaki disease,including clinical manifestations and laboratory examinations,in order to impove early-diagnosis. Methods Retrospective data from 21 cases of KD in infants was analysed,compared with 20 cases of KD in children older than 1 year in the same period. Results Compared with 20 cases of KD in children older than 1 year,the incidence of some clinical features,such as BCG vaccination erythrocyte,symptoms in digestive system and nervous system at early period were significantly(P<0.05),while cervical lymphadenopathy was absent in 21 cases of KD in infants. The incidence of IKD cases in infants increased statistically(P<0.05),Laboratory results,such as PLT,and the level of CRP,ALB,CK-MB have no difference except WBC and Hb. The cases of KD in infants have higher in WBC,but lower in Hb (P<0.05).More cases of KD with hepatic injury or coronary artery aneurysm appear in infants(P<0.05). Conclusion IKD cases and coronary artery aneurysm are more common in infants with KD.Not only the manual clinical features,but also BCG vaccination erythrocyte,symptoms in digestive system and nervous system and the level of WBC,Hb,PLT,CRP,ESR,ALT in time would be provide a clue for early diagnosis.Then completing the examination of coronary artery at the right time is necessary.

Key words: Infant, Kawasaki disease, Clinical manifestation, Hematology characteristic

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