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临床输血与检验

临床输血与检验 ›› 2019, Vol. 21 ›› Issue (5): 474-476.DOI: 10.3969/j.issn.1671-2587.2019.05.008

• 临床输血 • 上一篇    下一篇

青藏高原地区大量输血治疗后患者部分检验指标检测值变化及相关因素研究

赵铁民, 吴晓艳   

  1. 810000 西宁,青海红十字医院输血科
  • 收稿日期:2018-08-31 出版日期:2019-10-20 发布日期:2019-10-29
  • 作者简介:赵铁民（1969-）,男,回族,湖南湘潭人,副主任检验师,学士,主要从事输血研究工作,（Tel）13309710588。

Changes in Detection Values of Some Test Indicators and Related Factors in Patients after Massive Tlood Rransfusion Treatment in Tibetan Plateau

ZHAO Tie-min, WU Xiao-yan   

  1. Qinghai red cross hospital,Qinghai Xining 810000
  • Received:2018-08-31 Online:2019-10-20 Published:2019-10-29

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摘要： 目的 研究青藏高原地区大量输血治疗后患者部分检验指标检测值的变化及相关因素。方法 在2017年5月~2018年4月,选择在本院进行大量输血治疗的患者共72例,作为观察组,将同期72例在平原地区接受大量输血治疗的72例患者作为对照组,对比两组患者的7项输血常规检验指标,并分析其检测值的变化及其相关因素。结果 输血治疗结束后观察组的血小板（PLT）、血清钙（Ca2+）、凝血酶原时间（PT）和活化部分凝血活酶时间（APTT）与对照组比较,差异有统计学意义（P<0.05）,两组患者的血清钾（K+）、血清钠（Na+）、血浆纤维蛋白原（FIB）等指标比较,差异无统计学意义（P>0.05）。结论 高原地区大量输血治疗的过程中易出现不良病症,因此在青藏高原地区对患者进行大量输血治疗时,应当对检测值变化及其因素进行分析,以提前采取有效措施进行预防,进而减少并发症的出现,提高患者的治疗效果。

关键词: 青藏高原地区, 大量输血, 检验指标, 变化, 相关因素

Abstract: Objective To study the changes and related factors of some test indexes after massive blood transfusion in Tibetan Plateau.Methods From May 2017 to April 2018,72 patients undergoing massive blood transfusion in our hospital were divided into two groups. 72 patients who received massive blood transfusion in plain area in the same period weretaken as the control group. The seven routine blood transfusion indexes of the two groups were compared,and the changes of the detection values and the related factors were analyzed.Results Platelet （PLT） level and serum calcium（Ca2+）were measured in the observation group after blood transfusion therapy,the level of serum potassium （K） and serum sodium（Na+） were significantly different between the two groups （P<0.05）,the level of prothrombin time （PT）,activated partial thromboplastin time （APTT） was significantly higher than that of the control group （P<0.05）. There was no significant difference in plasma fibrinogen （FIB） （P>0.05）.Conclusion In the course of massive blood transfusion treatment in the plateau area,it is easy to appear adverse diseases. Therefore,the factors of the change of the detection value should be analyzed when the patients are treated with massive blood transfusion in the Tibetan Plateau area. Effective measures can be taken to prevent them in advance,thereby reducing the incidence of complications. to improve the therapeutic effect of patients.

Key words: Tibetan Plateau, Massive transfusion, Test index, Change, Related factors

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