• 中国科学论文统计源期刊
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临床输血与检验 ›› 2020, Vol. 22 ›› Issue (2): 138-141.DOI: 10.3969/j.issn.1671-2587.2020.02.007

• 采供血管理 • 上一篇    下一篇

唐山市献血人群弓形虫抗体检测和输血残余风险分析

张秀红   

  1. 063000 唐山市中心血站献血后资料管理科
  • 收稿日期:2018-12-20 出版日期:2020-04-20 发布日期:2020-04-16
  • 作者简介:张秀红(1972-),女,河北唐山人,主管护师,本科,主要从事献血与输血方面研究,(Tel)15162225517 (E-mail) jiagz1980@163.com。

Detection of Antibodies Against Toxoplasma Gondii in the Blood Donors and Its Risk Analysis of Residual Blood Transfusion

ZHANG Xiu-hong   

  1. Tangshan City Center Blood Station, Tangshan 063000
  • Received:2018-12-20 Online:2020-04-20 Published:2020-04-16

摘要: 目的 观察唐山市献血人群的弓形虫抗体检测结果及输血残余风险。方法 对唐山市血站308 024份血液标本进行弓形虫IgG抗体、IgM抗体检测,分析弓形虫抗体阳性献血人群的分布特征、危险因素以及输血残余风险。结果 唐山市献血人群的弓形虫抗体阳性3 453例 (1.14%),且呈逐年上升趋势(由2013年的0.92%上升到2018年1~6月的1.30%)(χ2=32.449,P<0.05);喜生食者、常接触动物者、重复献血者的抗体阳性率较高,分别为3.78%、2.85%、2.14%,且为献血人群弓形虫抗体阳性的独立危险因素(P<0.05)。献血人群弓形虫输血残余总风险为9.39×10-6,且喜生食者的输血残余风险(37.33×10-6)高于不常生食(5.57×10-6);常接触动物者的输血残余风险(40.06×10-6)高于不常接触动物者(4.83×10-6);首次献血者的输血残余风险(14.30×10-6)高于重复献血者(6.79×10-6)(P<0.05)。结论 本市献血人群弓形虫抗体阳性率较高,且有逐年上升趋势,经常生食和经常接触动物两类献血人群的弓形虫输血残留风险较高,可能给唐山市血液安全带来了潜在威胁。

关键词: 献血人群, 弓形虫抗体调查, 输血残余风险

Abstract: Objective To observe the antibody prevalence of Toxoplasma gondii in blood donors and analyze the residual risk of blood transfusion in Tangshan City. Methods A total of 308,024 blood samples were tested for IgG and IgM antibodies to T. gondii. The distribution characteristics, risk factors and residual risk of blood transfusion were analyzed. Results There were 3 453 cases (1.14%) of blood donors who were found to be positive for Toxoplasma antibodies, and the frequency trends to be increasing (from 0.92% in 2013 to 1.30% in 2018) (χ2=32.449, P<0.05); the positive rates were high in those with undercooked meat consumption, frequent contact to animals and repetitive blood donations(3.78%, 2.85% and 2.14%, respectively). The total risk of Toxoplasma transfusion residue in the blood donors was 9.39×10-6, and that in those with raw/undercooked food consumption (37.33×10-6) was high (5.57×10-6). The risk of blood transfusion residue in those with frequent contact to animals (40.06×10-6) and repeated donations (14.30×10-6) was elevated compared with the other donors (P<0.05). Conclusion The antibody prevalence of Toxoplasma gondii in blood donors seems to be increasing. The high risk of T. gondii residue in blood donors with raw/undercooked foods and/or frequent contact to animals may be a potential threat to blood safety .

Key words: Blood donation, Toxoplasma infection, Risk of residual blood transfusion

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