血浆置换在自身免疫性疾病肾脏损伤中的治疗作用

doi:10.3969/j.issn.1671-2587.2022.02.026

临床输血与检验 ›› 2022, Vol. 24 ›› Issue (2): 264-267.DOI: 10.3969/j.issn.1671-2587.2022.02.026

血浆置换在自身免疫性疾病肾脏损伤中的治疗作用

刘奇, 张彬

400038 陆军军医大学第一附属医院输血科

收稿日期:2021-10-15 发布日期:2022-04-12
通讯作者: 张彬,男,讲师,主治医师,博士,主要从事血液净化治疗相关临床和基础研究,（E-mail）binzhang301@163.com。
作者简介:刘奇（1992-）,男,实验师,学士,主要从事血液制备及保存研究,（E-mail）403578448@qq.com。

Received:2021-10-15 Published:2022-04-12

摘要/Abstract

摘要： 自身免疫性疾病会引起患者免疫功能紊乱,常常累及肾脏,目前针对自身免疫性疾病尚无特效药物。近年来随着血浆置换技术的发展及成熟,血浆置换联合其他综合治疗可迅速清除自身抗体,改善自身免疫性疾病患者的病情,逐渐得到认可。本文结合美国血浆置换学会最新发布的临床实践治疗性单采术应用指南,综合国内外研究报道,在众多的自身免疫性疾病中选取了最容易造成肾脏损伤的系统性红斑狼疮、抗中性粒细胞胞质抗体相关性血管炎和抗肾小球基底膜病,探讨血浆置换在自身免疫性疾病肾脏损伤中的修复作用,为今后血浆置换对自身免疫性疾病引起肾脏损伤的治疗提供更多的临床参考。

关键词: 血浆置换, 自身免疫性疾病, 自身抗体, 肾脏损伤, 肾脏修复

中图分类号:

R457

刘奇, 张彬. 血浆置换在自身免疫性疾病肾脏损伤中的治疗作用[J]. 临床输血与检验, 2022, 24(2): 264-267.

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血浆置换在自身免疫性疾病肾脏损伤中的治疗作用

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