Abstract: Objective To explore the differences of anemia rate and iron metabolism indexes among patients with different chronic kidney disease （CKD） stages. Methods 205 patients with CKD,admitted into our hospital from 2016 to 2017,were recruited in this study. Red blood cell （RBC）,Hb,HCT,SF,SI,STF,UIBC and TIBC were measured respectively in the patients with various CKD stages. The statistical analyses were performed in terms of anemia rate and iron metabolism indexes among CKD 2,3,4 and 5 stages. Results The anemia rates in the indicated CKD stages presented respectively： CKD 2,14.8%; CKD 3,44.8%; CKD 4,79.1%; CKD 5,98.7%. There were significant differences in anemia rate and iron metabolism indexs among the five CKD stages （P<0.05）. From CKDs 2 to 5,the levels of RBC and Hb decreased with disease progression .Compared with other stages,SF was significantly increased in CKD5,while STF was lower in CKD5 than in other stages. In CKD4 and 5,SI significantly decreased. Conclusion CKD patients with different stages had different degrees of anemia,which was closely related to iron metabolism. Moreover,there were differences in anemia and iron metabolism,which were relevant with the severity of the disease and may be helpful for clinical diagnosis and treatment.

Key words: Iron metabolism, CKD, Anemia