Abstract: Objective To explore the effects of the nursing intervention before blood transfusion on prevention of adverse transfusion events in patients with hematologic diseases. Methods A total of 1 112 patients whohad received transfusion therapy in haematology department in 2015 were randomly divided into two groups,the control group （n= 1 056） and experimental group （n=1 056）. The control group was administered with traditional nursing modelwhereas the experiment group was given psychological counseling,nursing,and psychological analysis in addition to the routine nursing. The incidence of adverse transfusion events between the two groups were compared indifferent blood products.Results A total of 123 patients with adverse transfusion events in the two groups,with a frequency of 5.82% . The incidence rate inthe control group was significantly higher than that of the experiment group （7.39% vs 4.26%,P<0.05）. There was no difference between the two groups with frozen plasma transfusion（P>0.05） and cryoprecipitatedantihemophilic factors transfusion（P>0.05）. Adverse transfusion events of the experiment group with plateletand erythrocytetransfusions were obviously lower than those of the control group（P<0.05）,especiallyof the patients with multiple myeloma. Conclusions Nursing intervention before blood transfusion is indispensable forpatients with hematologic diseases with blood component therapy,particularly with platelet orerythrocyte transfusion.

Key words: Hematologic disease, Nursing intervention, Adverse transfusion events, Risk of blood transfusion