Abstract: Objective To explore the value of CRP/PA ratio in the early clinical diagnosis and treatment of chronic obstructive pulmonary disease. Method sCRP,PA,RDW,WBC,N% and other indicators were detected before and after treatment,as well as serum C-reactive protein (CRP) and prealbumin (PA ratio) in COPD of 50 patients with acute exacerbation of patients with stable COPD group,50 cases in the control group in the Ma'anshan Market Center Hospital from March 2015 to March 2016. Results CRP was significantly higher in the study group before treatment than that in the control group after treatment,CRP is still higher than the control group after treatment (P<0.05); the study group before treatment was significantly lower PA than that of after treatment and control group after treatment control group (P<0.05); C-reactive protein (CRP) and prealbumin (PA) ratio of 0.853 the study group before treatment; the positive rate of CRP (84%),PA (76%),WBC (26%),RDW (62%),N% (72%) was significantly higher than that after treatment and control group (P<0.01). Conclusion CRP/PA ratio has an important guiding significance for the early diagnosis of AECOPD,which provides strong evidence for effective medical clinical application of antibiotics.

Key words: Chronic lung disease, Acute exacerbation, Ratio, Positive detection rate