Abstract: Objective Toevaluate the clinical effect of advanced autologous apheresis （AAA） in avoiding allogeneic blood transfusion in idiopathic scoliosis surgery. Methods We reviewed 32 idiopathic scoliosis patients who underwent elective surgery at a single hospital from July 2017 to July 2018. The patients were divided into AAA group and control group. We compared general information, surgical characteristics, autologous red blood cells （RBC） collecting amount, allogeneic RBC and plasma transfusion volume, laboratory data including RBC count, hemoglobin （Hb） level, hemotocrit （HCT）, platelet count （PLT） in preoperative 3 days, operating time, postoperative 1 day and 3 days. Results Two cohorts had no differences in general information, surgical characteristics and preoperative levels of RBC, Hb, HCT and PLT （P>0.05）. Compared to control group, autologous blood collecting amount in AAA group was much higher（P<0.05）, and allogeneic RBC transfusion volume was significantly reduced（P<0.05）. After autologous blood collecting, RBC, Hb and HCT levels of patients were lower than before（P<0.05）, and no decline in PLT levels（P>0.05）. Two cohorts had no differences in postoperative in RBC, Hb, HCT and PLT levels（P>0.05）. Conclusion AAA can reduce allogeneic transfusion in idiopathic scoliosis patients.

Key words: Advanced Autologous, Apheresis, Erythrocyte Apheresis Idiopathic Scoliosis