Abstract: Objective To retrospectively investigate the patients for the emergency rescue blood transfusion who presented positive antibodies and to evaluate the effect of "recommended regimens" in clinical transfusion.Methods Inform-ation of the individuals was collected in Handan area from June 2014 to May 2016, and irregular antibodies were screened and patients with positive antibodies for emergency rescue blood transfusion were evaluated for the application effect based on "recommended regimens ".Results Twenty cases of emergency rescue group and 31 cases of blood transfusion showed a total efficiency of 77.4%, following 31 times of transfusion with 126 U red blood cells (4 U on average). Eighty three cases received 137 times of transfusion after specific antibodies were identified,with a total efficiency of 86.9%. No obvious difference was seen between the two groups（χ²=1.78,P>0.05）.Conclusion It is relatively safe for the patients with positive irregular antibodies who need emergent blood transfusion to use the same blood type and negative blood cross-matching, or to use O type and negative cross-matching. The present investigation suggests that there is no difference of blood transfusion efficiency between the patients with emergent transfusion and normal transfusion.

Key words: Irregular, antibody, screening, Antibody, specificity, Emergency, rescue, transfusion