• 中国科学论文统计源期刊
  • 中国科技核心期刊
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  • 日本科学技术振兴机构数据库(JST)
临床输血与检验

临床输血与检验 ›› 2016, Vol. 18 ›› Issue (5): 475-477.DOI: 10.3969/j.issn.1671-2587.2016.05.024

• 临床检验研究 • 上一篇    下一篇

多次单采血小板献血者外周血网织血小板百分比水平的变化*

周爱国, 李继红, 周宁, 孟德伍, 祝峰, 范恩勇   

  1. 225001 江苏省扬州市第一人民医院检验科（周爱国）; 武警江苏省总队医院检验科（李继红,周宁,孟德伍,祝峰）; 扬州市中心血站质量技术科（范恩勇）
  • 收稿日期:2016-05-12 出版日期:2016-10-20 发布日期:2017-05-19
  • 通讯作者: 范恩勇,男,本科,副主任技师,（Tel）18936220169（E-mail）fanenyong@163.com。
  • 作者简介:周爱国（1973-）男,江苏扬州人,副主任技师,学士,主要从事临床检验工作,（Tel）18936220169。
  • 基金资助:
    *本课题受扬州市科技发展计划项目（No; YZ2014225）资助

The Percentage Variation of Platelets in Multiple Donator Apheresis Platelets in Peripheral Blood Reticulocytes

ZHOU Ai-guo, Li Ji-hong, Zhou-ning, et al   

  1. Department of Clinical Laboratory,Yangzhou No.1 People’s Hospital,Yangzhou 225012
  • Received:2016-05-12 Online:2016-10-20 Published:2017-05-19

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摘要： 目的 了解单采血小板献血者外周血网织血小板百分比水平的变化情况。方法 按照单采血小板捐献情况分为2组,实验组为参加过单采血小板的献血者153例,对照组为以往无献血史,首次来血站献血且符合献血条件,共189例,利用全自动血球分析仪检测WBC、RBC、Hb、HCT、PLT、PDW、PCT、MPV及IPF比例等项目。结果 与对照组相比,实验组中男性献血者WBC、PCT的差异均无统计学意义（P>0.05）,RBC、Hb、HCT、PLT明显升高,有统计学意义（P<0.05）,PDW、MPV、IPF下降,有统计学意义（P<0.05）;实验组中女性献血者WBC、RBC、Hb、HCT、PLT、PCT、MPV的差异均无统计学意义（P>0.05）,PDW、IPF明显升高,有统计学意义（P<0.05）。结论 多次进行单采血小板捐献,对于男性献血者除加快RBC、PLT的骨髓造血功能外,并未加速IPF上升,相反促进PLT成熟。对于女性献血者则由于自身早期的生理性周期性失血,女性献血者的RBC、PLT等指标已受自身免疫负反馈调节而耐受,但对于多次捐献血小板的女性献血者,可能血小板生成能力较男性献血小板者增加有关。

关键词: 网织血小板, 单采血小板, 骨髓

Abstract: Objective To understand reticulated platelet level changes in apheresis platelet donors. Methods The platelets donators were divided into experimental group (A) and control group(B). Group A comprised 153 cases of apheresis platelet donors and group B included 189 cases without the experience of blood donation. Automated blood analyzer was used for testing WBC,RBC,Hb,HCT,PLT,PDW,PCT,MPV and IPF proportions and other items. Results No significant difference was seen of WBC and PCT（P>0.05） in the male blood donors in Group A,whereas RBC,Hb,HCT,and PLT were obviously elavated（P<0.05）and PDW, MPV,and IPF decreased（P<0.05）. Comparatively, WBC,RBC,Hb,HCT,PLT,PCT,and MPV did not give rise to any change in female donors（P>0.05）whereas PDW and IPF were significantly increased（P<0.05）. Conclusion Repeated apheresis platelet donations may accelerate RBC and PLT rather than IPF production in bone marrow,and promote the PLT maturity. Female donors, due to the periodic blood loss of RBC,may have a higher capacity of platelets generation capacity than males.

Key words: Reticulated platelets, Apheresis platelets, Bone marrow

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