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临床输血与检验

临床输血与检验 ›› 2019, Vol. 21 ›› Issue (1): 85-87.DOI: 10.3969/j.issn.1671-2587.2019.01.028

• 临床检验 • 上一篇    下一篇

芜湖地区女性在妊娠各期甲状腺功能参考值调查

李振, 刘福荣, 乔李, 马军民   

  1. 241000 安徽省芜湖市第一人民医院（李振,刘福荣）;
    妇产科（乔李）;
    内分泌科（马军民）
  • 收稿日期:2018-10-20 出版日期:2019-02-20 发布日期:2019-01-28
  • 作者简介:李振（1984-）,男,安徽宿州人,主管检验师,硕士研究生,主要从事临床免疫工作,（Tel）15155389958（ E-mail）lz441244cxl@163.com。

Investigation on the Reference Range of Thyroid Gland in Pregnant Women in Wuhu Area

LI Zhen, LIU Fu-rong, QIAO Li, et al   

  1. The First People's Hospital of Wuhu,Anhui 241000
  • Received:2018-10-20 Online:2019-02-20 Published:2019-01-28

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摘要： 目的 分析芜湖地区健康女性妊娠期甲状腺变化,建立妊娠早、中、晚三期甲状腺功能的参考范围。方法 选取妊娠早、中、晚期女性共计379例,采用化学发光免疫分析法分期检测TSH 、FT3和FT4。另选取118例健康非妊娠女性作为对照组,分析TSH 、FT3、FT4三项指标在各组之间的差异。结果 血清TSH、FT3、FT4在妊娠早期的参考范围分别为0.38~4.07 mIU/L、3.55~5.30 pmol/L、11.35~17.43 pmol/L;妊娠中期的参考范围分别为0.41~4.14 mIU/L、2.99~5.20 pmol/L、10.48~17.79 pmol/L;妊娠晚期的参考范围分别为0.54~4.54 mIU/L、2.88~4.86 pmol/L、9.27~16.47 pmol/L。结论 芜湖地区健康妊娠期孕妇甲状腺主要血清学指标在不同孕期存在明显差异,应建立不同孕期的参考范围。

关键词: 妊娠, 甲状腺激素, 参考范围

Abstract: Objective To establish the reference range of thyroid hormone at different stages of pregnancy,we analyzed the serum levels of major thyroid markers in healthy women in Wuhu area during pregnancy. Methods A total of 379 women during the different pregnancy were selected to detect TSH,FT3 and FT4 by Chemiluminescence Immunoassay. Another 118 healthy non-pregnant women were selected as control group。Analysis of TSH,FT3,FT4 three indicators in the different stages. Results Serum TSH,FT3,FT4 in the early pregnancy of the reference range were 0.38~4.07 mIU/L,3.55~ 5.30 pmol/L,11.35~17.43 pmol/L. The reference range in the middle of pregnancy was 0.41~4.14 mIU/L,2.99~5.20 pmol/L,10.48~17.79 pmol/L. In the late pregnancy reference range were 0.54~4.54 mIU/L,2.88~4.86 pmol/L,9.27~16.47 pmol/L. Conclusion The main serological indexes of thyroid in healthy pregnant women in Wuhu area were significantly different at different gestational periods,and we should establish a reference range for different pregnancies.

Key words: Pregnancy, Thyroid hormone, Reference range

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