体外膜肺氧合支持下的输血策略

doi:10.3969/j.issn.1671-2587.2021.04.002

临床输血与检验 ›› 2021, Vol. 23 ›› Issue (4): 412-415.DOI: 10.3969/j.issn.1671-2587.2021.04.002

体外膜肺氧合支持下的输血策略

司念, 李可, 魏晴

430030 武汉华中科技大学同济医学院附属同济医院输血科

收稿日期:2021-05-13 出版日期:2021-08-20 发布日期:2021-08-18
通讯作者: 李可,男,医学博士,主管技师,主要从事血型抗原与疾病病理生理、血液系统疾病基因组学相关基础研究,（E-mail）likelff1@hust.edu.cn。共同通信作者：魏晴,女,医学博士,主任医师,主要从事临床输血及Rh血型的分子生物学基础研究,（E-mail）weiqing@hotmail.com。
作者简介:司念（1995-）,女,河南商丘人,医学硕士在读,主要从事输血相关免疫机制的研究,（E-mail）sinian15002590731@163.com。

Received:2021-05-13 Online:2021-08-20 Published:2021-08-18

摘要/Abstract

摘要： 体外膜肺氧合（Extracorporeal membrane oxygenation, ECMO）是一种改良的心肺替代通路,是挽救呼吸功能或心肺功能衰竭患者生命的支持技术,作为一种人工膜肺和血泵为心肺衰竭患者提供气体交换与血液循环。在ECMO治疗期间由于人工管道和人体内部结构的巨大差异,会对血液造成多种影响：（1）红细胞（red blood cell,RBC）膜改变引起溶血;（2）血小板破坏增多导致血小板数量减少和功能障碍,以及凝血因子水平降低而造成出血;（3）血流动力学改变,形成血栓,引起多种并发症。因而在ECMO支持治疗中输血必不可少,而各国对于血液成分输注阈值有所不同,随着研究不断进展,输注阈值也在发生变化,最佳的输血策略值得我们深入探究。

关键词: 输血, 体外膜肺氧合, 出血, 凝血障碍, 输血策略

中图分类号:

R457

司念, 李可, 魏晴. 体外膜肺氧合支持下的输血策略[J]. 临床输血与检验, 2021, 23(4): 412-415.

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体外膜肺氧合支持下的输血策略

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