石墨烯电化学生物传感器在肿瘤检测中的研究进展*

doi:10.3969/j.issn.1671-2587.2022.04.025

临床输血与检验 ›› 2022, Vol. 24 ›› Issue (4): 539-544.DOI: 10.3969/j.issn.1671-2587.2022.04.025

• 综述 • 上一篇

石墨烯电化学生物传感器在肿瘤检测中的研究进展^*

梁颖, 伍仕敏

430010 武汉,长江航运总医院/武汉脑科医院检验科

收稿日期:2022-01-26 出版日期:2022-08-20 发布日期:2022-08-19
通讯作者: 伍仕敏,女,主任技师,博士,主要从事实验室管理与临床检验诊断研究,（E-mail）mintyrain@126.com。
作者简介:梁颖（1990-）,女,湖北十堰人,主管技师,硕士,主要从事生物传感与临床检验诊断研究,（E-mail）406827677@qq.com。
基金资助:
*本课题由湖北省武汉市卫生计生科研基金项目（No.WX17Q41）资助

Received:2022-01-26 Online:2022-08-20 Published:2022-08-19

摘要/Abstract

摘要： 肿瘤是严重威胁人类健康的疾病之一,降低肿瘤病死率的主要途径是早期诊断和治疗,因此对肿瘤相关物质进行准确检测具有重要的临床意义。随着电化学生物传感器和纳米材料的迅速发展,基于纳米材料石墨烯构建的电化学传感器可实现对肿瘤相关指标的检测,且具有检测灵敏度高、特异性强等优点。本文简要介绍石墨烯的理化特性和电化学传感器的工作原理,结合近几年石墨烯电化学生物传感器在肿瘤相关指标检测中的文献报道,重点综述石墨烯电化学生物传感器在肿瘤检测中的应用,包括常见肿瘤标志物、相关癌基因、肿瘤细胞、肿瘤相关microRNA和其他肿瘤相关指标的检测。

关键词: 肿瘤, 肿瘤标志物, 电化学传感器, 纳米材料, 石墨烯

中图分类号:

O657.1
R73

梁颖, 伍仕敏. 石墨烯电化学生物传感器在肿瘤检测中的研究进展^*[J]. 临床输血与检验, 2022, 24(4): 539-544.

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石墨烯电化学生物传感器在肿瘤检测中的研究进展^*

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