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临床输血与检验

临床输血与检验 ›› 2017, Vol. 19 ›› Issue (2): 132-135.DOI: 10.3969/j.issn.1671-2587.2017.01.011

• 临床输血 • 上一篇    下一篇

广西中北部地区不规则抗体筛选分析

唐玉杰, 施丽, 唐生明   

  1. 541001 广西桂林医学院附属医院输血科（唐玉杰,唐生明）; 新疆伊犁州友谊医院输血科（施 丽）
  • 收稿日期:2016-10-13 出版日期:2017-04-20 发布日期:2017-04-24
  • 通讯作者: 唐玉杰,女,主管技师,（E-mail）huangw_j168@163.com。
  • 作者简介:唐玉杰（1976-）,女,广西人,主管技师,硕士,主要从事输血工作,（Tel）18102268689。

Analysis of Irregular Antibody Screening of the North Central Area of Guangxi Province

TANG Yu-jie, SHI Li, TANG Sheng-ming   

  1. Blood Transfusion Department of Affiliated Hospital of Guilin Medical College 5410012
  • Received:2016-10-13 Online:2017-04-20 Published:2017-04-24

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693

被引次数

1

摘要： 目的 通过本院输血患者不规则抗体筛选的分析,探讨其对安全输血的临床指导价值。方法 选择2012年2月~2016年2月在本院输血的患者38 722例,根据患者不规则抗体筛选的分析,筛选出阳性患者并做特异性分析,交叉配血使其能够安全有效的输血。结果 ①38 722例患者作不规则抗体筛选,阳性患者278例,占0.717%。其中男性患者阳性率为0.214%,低于女性患者（0.503%）,差异有统计学意义（P<0.05）。②无输血史及无妊娠史的不规则抗体患者阳性率为0.114%,低于有输血史或有妊娠史的不规则抗体阳性率（1.587%）,差异有统计学意义（P<0.05）。③278例不规则抗体患者中,特异性抗体患者128例（46%）,其中RH患者98例（35.3%）,MNS患者20例（7.2%）及其他特异性抗体患者10例（3.6%）;非特异性抗体患者150例（54%,150/278）,其中冷自身抗体患者68例（24.5%）,其他非特异性抗体患者82例（29.5%）。结论 ①广西中北部地区不规则抗体筛选结果分析与全国其他各地相差不大,属于正常情况。②通过输血前不规则筛选指导患者输血配血,对阳性患者进行特异性分析和交叉配血,在安全输血上具有重要的临床指导意义。

关键词: 不规则抗体, 临床输血, 筛选

Abstract: Objective By analyzing irregular antibody screening of patients with blood transfusions,we explored its significance in blood transfusion safety and regional clinical guidance.Methods 38 722 patients with blood transfusions were studied from February 2012 to February 2016and among them positive irregular antibodies were screened and specificity was analyzed for safe and effective transfusion. Reasults 278 cases of positive irregular antibodies were found in the patients,which accounted for 0.717% （278/38 722）. Among them 83 males with a positive rate of 0.214% （83/38 722）,and 195 females with a positive rate of 0.503% （195/38 722）were observed. Female patients had a significantly high positive rate when compared with male patients（P<0.05）. The positive incidence of 0.114% （26/22 846）in the patients with history of blood transfusion and pregnancy was lower than that in control （1.587%,252/15 876）（P<0.05）.. . Among the 278 patients with irregular antibodies,128 （46.0%） patients presented specific antibodies,including 98 cases of RH （35.3%,98/278）,20 cases of MNS patients （7.2%,20/278）,and 10 cases of others（3.6%,10/278）. 150 （54%,150/278） patients had non-specific antibodies,,68 had cold antibodies （24.5%,68/278）,and 82（29.5%,82/278） carried other non-specific antibodies.Conclusion Analysis of the north central area of Guangxi province are similar with the other regions,under the normal conditions. Through the screening before blood transfusion,the patients with positive irregular antibodies should be analyzed for blood cross matchingand transfusion safety.

Key words: Irregular antibody, Clinical transfusion, Screening

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