Abstract: Objective To investigate the proper screening mode for floating and fixed blood donations. Methods The experiment was conducted in two stages. In the first stage,donors were selected from first blood donation in the streets and the fixed donors of university students,workers and employees of the enterprises and governments from 2011-2013. In the second stage,donors were only selected from the fixed donors in 2014.The primary screening and re-tests included Hb,ALT and HBsAg. Results Compared with the fixed donors,those of the first blood donation in the streets had a high defective rates of Hb,ALT and HBsAg screening tests,while the defective rate of HB tests were lower in the workers of enterprises than in the university students. Primary screening tests were not implemented in the male workers of enterprises and public institutes and university students. No difference of the qualification rates was noted among the three populations within three years. Conclusion A safe and fixed population of blood donation should be grouped,and optimized preliminary screening mode should be used to reduce the unhealthy emotions of donators and increase the work efficiency.

Key words: Fixed blood donors, Blood test, Blood safety, Screening mode