Abstract: Objective To explore the levels of serum total cholesterol （TC） and hemoglobin （Hb） in different stages of chronic lymphatic thyroiditis（CLT） in female patients and its clinical significance. Methods 119 female patients with CLT were divided into 3 groups according to serum TSH levels. Group A （patients with transient hyperthyroidism,TSH<0.27 IU/ml）; Group B （patients with normal serum TSH,TSH0.27-4.2 IU/ml）; and Group C （patients with hypothyroidism,TSH>4.2 IU/ml）. Another 36 persons,who showed normal condition after health examinations swere selected as controls. The serum levels of TSH,TC and Hb were detected and compared in the four groups. Correlations of TSH with TC and Hb were evaluated in patients with CLT. Results The serum TC level was significantly higher in Group B and Group C than in normal controls. The level of TC was notably lower in Group A than in the other 3 groups （P<0.05）. The serum level of Hb was significantly lower in Group A and Group C than in normal controls（P<0.05）. In patients with Hashimoto′s thyroiditis,TSH was positively correlated with TC（r=0.572,P<0.001）,but not with Hb（r=0.256,P>0.05）.Conclusions There exists alteration of TC and Hb in different stages of chronic lymphatic thyroiditis in female patients,and timely laboratory survelliance would be necessary.

Key words: Chronic lymphatic thyroiditis, TSH, Total Cholesterol, Hemoglobin