Abstract: Objective To explore hemoglobin critical value for pediatric patients and patients with neonatal transfusion of red blood cell，and used it in clinical transfusion management of critical value. Methods Respectively threshold for starting the transfusion of red blood cells were collected in children hospitalized with leukemia，cancer，tissue cells and bone marrow transplantation before and after the children，pediatric intensive care unit，neonatal medical children，children with other children with medical and emergency medicine，and statistically analysed，based on on the study，children with partial internal medicine and neonatal infusion of red blood cells critical value was established，and used in hospital transfusion management. Results Eight medical group average Hb was 76.39 g/L for transfusion of red blood cells，transfusion of red blood cells of newborn group average Hb was 101.30 g/L. Through discussion by the hospital transfusion management committee，hemoglobin critical value is set as 75 g/L for pediatric medical transfusion of red blood cell，the newborn transfusion of red blood cell hemoglobin critical value as 100 g/L，new critical value will be released to the floor of each department. Release of new critical value before and after transfusion of red blood cells per patient fell by 0.2 U，neonatal infusion of red blood cells per patient fell 0.1 U. Conclusion Through the formulation of red blood cells infusion critical value，and on the floor，can effectively reduce the amount of red blood cell transfusion in children，save blood resources，improve children blood transfusion safety.

Key words: Children, Newborn , Critical value of hemoglobin