Abstract: Objective To select matching red blood cells and promote hemoglobin level for anemia patient with autoantibody caused by G6PD deficiency. Methods Blood group typing, antibody screening and cross matching were tested by micro column gel method. Results Autoantibody was identified in the patient, which caused interference with main side in cross-match. Two units of RBC, whose main side agglutination intensity was lower than or similar to self-control, were selected after cross-matching multiple donors, and transfused to the patient. Conclusions Main side agglutination due to autoantibody is not an absolute contraindication for transfusion, and the hemoglobin of patient is effectively improved after transfusion of 1.5 U RBC.

Key words: Autoantibody, Iso-antibody, Transfusion, efficacy