• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2016, Vol. 18 ›› Issue (6): 586-590.DOI: 10.3969/j.issn.1671-2587.2016.06.025

• Original Articles • Previous Articles     Next Articles

The Diagnostic Significance of Red Blood Cell Volume Distribution Width in Non-ST-segment Elevation of Acute Coronary Syndrome

LAI Yong-kun, LV Wei-biao, LI Jin-rong, et al   

  1. Department of Clinical Laboratory,the First People's Hospital of Shunde area,Shunde528300
  • Received:2016-04-06 Online:2016-12-20 Published:2016-12-23

Abstract: ObjectiveTo explore the predictive value of non-ST-segment elevation of acute coronary syndrome(NSTE-ACS)by detection of red blood cell volume distribution width (RDW)for determination of the cut off point. MethodsFrom January 2014 to June 2015,146 NSTE-ACS cases were collected in observation group,and 84 individuals were taken as control with non coronary heart disease confirmed by coronary angiography. The complete blood counting,cardiac troponin I (cTnI),and blood lipid wee tested. ResultsTC,LDL-C,cTnI,and RDW of NSTE-ACS group was higher than that of the control group,with a higher ratio of high blood pressure history or diabetes history(P<0.05). The RDW in those with the artery lesions of three branches was higher than with the single artery lesion and double branch lesions(P<0.05). RDW and cTnI were positively correlated(r=0.298,P<0.05). RDW receiver operating characteristic(ROC)curve analysis whowed thatthe best cut-off point of RDW for prediction of NSTE-ACS was 11.93%,the area under the ROC curve was 0.845(95% CI:0.792~0.898,P<0.05),specificity was 82.90%,and sensitivity was 72.62%. Patients with the RDW over 11.93% presented a higher mortality or non-fatal myocardial infarction within 30 days than those with the RDW below 11.93%(P<0.05). ConclusionRDW is associated with the degree of lesion in NSTE-ACS,and may be used as auxiliary diagnosis and prognosis of NSTE-ACS.

Key words: Red, blood, cell, distribution, width, Non-, ST-segment, elevation, acute, coronary, syndrome, Cardiac, troponin, I

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