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临床输血与检验

临床输血与检验 ›› 2017, Vol. 19 ›› Issue (1): 46-49.DOI: 10.3969/j.issn.1671-2587.2017.01.013

• 临床输血 • 上一篇    下一篇

抗-HCV筛查反应性献血者的确证结果分析*

李莉华, 韩雪峰, 马印图   

  1. 050071 河北省血液中心检验科（李莉华,韩雪峰）;
    解放军白求恩国际和平医院输血科（马印图）
  • 收稿日期:2016-09-06 出版日期:2017-02-20 发布日期:2017-03-02
  • 作者简介:李莉华（1971-）,女,河北石家庄人,副主任检验师,学士,主要从事输血相关传染病及血液安全方面的研究,（Tel）0311-87044310（E-mail）15931096399@163.com。
  • 基金资助:
    *本课题受河北省卫生和计划生育委员会指令性课题（No; ZL-20140122）资助

Confirmation of Anti-HCV Screening-Positive Donor Samples in Blood Center

LI Li-hua, HAN Xue-feng, MA Yin-tu   

  1. Department of Laboratory in Hebei Province Blood Center 050071
  • Received:2016-09-06 Online:2017-02-20 Published:2017-03-02

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摘要： 目的 分析无偿献血者抗-HCV筛查反应性标本的确证试验结果。方法 随机收集无偿献血者抗-HCV筛查反应性标本284例,采用免疫印迹法（WB）进行确证试验。将检测结果结合献血者基本资料进行数据分析。结果 对284例抗-HCV筛查反应性血液标本进行确证试验,其中：ELISA方法检测抗-HCV确证阳性率为49.82%;双试剂ELISA反应性与单试剂反应性标本确证阳性率的差异有统计学意义;初次献血者与重复献血者确证阳性率的差异、不同性别和不同年龄组确证阳性率的差异均有统计学意义。结论 采供血机构应开展筛查反应性献血者的确证试验,和/或补充试验,尤其是单试剂反应性的献血者和重复献血者,减少献血队伍的流失。

关键词: 抗-HCV, 免疫印迹法, 酶联免疫法

Abstract: Objective To analyze the confirmation test Results of anti-HCV screening-positive samples of the blood donors. Method The 284 anti-HCV screening-positive donor samples were collected randomly. Western blotting（WB） test was used to confirm the Results. The Results were evaluated based on the data of WB test and personal information of the blood donors. Result 49.82 percent of 284 cases of anti-HCV screening-positive donor samples were confirmed to be positvie. Compared with the confirmation Results of positive samples screened by two round ELISA and positive samples screened by single round ELISA ,significant statistical differences were noted in positive rates. The confirmed positive rates between initial and repeated blood donations,genders and ages revealed significant statistical differences. Conclusion Confirmation or additional tests should be carried out for screening-positive donors,particularly in those screened by single round ELISA and repeated blood donors.

Key words: Anti-HCV, Western Blot（WB）, ELISA

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