• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

临床输血与检验 ›› 2017, Vol. 19 ›› Issue (2): 129-131.DOI: 10.3969/j.issn.1671-2587.2017.02.010

• 临床输血 • 上一篇    下一篇

肿瘤患者化疗期间红细胞悬液输注疗效分析

谭金哲, 刘敏雪, 谭斌   

  1. 610041 成都,四川大学华西医院实验医学科
  • 收稿日期:2016-11-18 出版日期:2017-04-20 发布日期:2017-04-24
  • 通讯作者: 谭斌(1968-),女,副主任技师,主要从事输血的临床、教学、科研及管理工作,(Tel)13881948204(E-mail)tjz5108@163.com。
  • 作者简介:谭金哲(1985-),男,四川成都人,技师,主要从事临床输血检验相关工作,(E-mail)tjz5108@163.com。

Analysis of the Efficacy of Red Blood Cell Suspension Infusion During Chemotherapy for Tumor Patients

TAN Jin-zhe, LIU Min-xue, TAN Bin   

  1. Institute of Experimental Medicine,Sichuan University West China Hospital,Chengdu 610041
  • Received:2016-11-18 Online:2017-04-20 Published:2017-04-24

摘要: 目的 分析肿瘤患者化疗期间红细胞悬液输注的疗效,为临床化疗方案决策提供参考。方法 回顾性分析华西医院2012~2013年住院肿瘤患者化疗期间红细胞悬液输注情况。结果 未化疗组肿瘤患者输注红细胞悬液的有效率77.3%(58/75)略高于化疗组75.8%(141/186),但差异无统计学意义(P﹥0.05);经含铂方案化疗的肿瘤患者输注红细胞悬液有效率27.8%(22/79)明显低于非含铂方案化疗组41.1%(44/107),且差异有统计学意义(P<0.05)。结论 化疗会降低红细胞悬液输注疗效,含铂化疗药物对骨髓有抑制反应,大大降低肿瘤患者红细胞悬液的输注疗效。

关键词: 肿瘤, 化疗, 输血疗效, 含铂化疗药物

Abstract: Objective To investigate,so as to provide reference for clinical decision about chemotherapy regimens. To provide reference for clinical decision about chemotherapy regimens,we studied the curative effect of red blood cells infusion on tumor patients undergoing chemotherapy.Methods Retrospectively we analyzed red blood cells infusion of hospitalized tumor patients during chemotherapy in West China Hospital of Sichuan University from 2012 to 2013.Results Tumour patient transfusion of red blood cell suspension effective rate was 77.3%(58/75)is slightly higher in Chemotherapy group than that 75.8%(141/186)in nonchemotherapy group,but there is no statistical difference(P﹥0.05):The effective rate of transfusion of red blood cell suspension was (27.8% 22/79)significantly lower in platinum-based chemotherapy of tumor patient group than that in the nonplatinum-based chemotherapy group (41.1%,44/107),and the difference was statistically significant (P﹥0.05).Conclusion Chemotherapy can reduce the curative effect of red blood cells infusion,and platinum-based chemotherapy drugs also cause bone marrow inhibition reaction,which reduce the curative effect of red blood cells infusion in tumor patients.

Key words: Tumor, Chemotherapy, Effect, of, blood, transfusion, Platinum-based, chemotherapy

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