RDW、Cys-C与慢性阻塞性肺疾病患者继发肺动脉高压关系的研究

doi:10.3969/j.issn.1671-2587.2018.05.024

临床输血与检验 ›› 2018, Vol. 20 ›› Issue (5): 531-533.DOI: 10.3969/j.issn.1671-2587.2018.05.024

RDW、Cys-C与慢性阻塞性肺疾病患者继发肺动脉高压关系的研究

孙莹, 刘长春, 郝丽梅, 王佳, 王春玲

100028 北京,煤炭总医院干部医疗科

收稿日期:2018-04-07 出版日期:2018-10-20 发布日期:2018-09-27
作者简介:孙莹（1981-）,女,吉林人,主治医师,硕士,主要从事慢性阻塞性肺疾病研究,（Tel）13560188581。

Red Blood Cell Distribution Width,Cys-C Secondary Pulmonary Hypertension in Patients with Chronic Obstructive Pulmonary Disease and its Severity of Predictive Value

SUN Ying, LIU Chang-chun, HAO Li-mei, etal

China Meitan General Hospital,Beijing 100028

Received:2018-04-07 Online:2018-10-20 Published:2018-09-27

摘要/Abstract

摘要： 目的探讨红细胞分布宽度（RDW）、Cys-C对慢性阻塞性肺疾病患者继发肺动脉高压及其严重程度的预测价值。方法从本院于2012年4月~2015年6月期间收治的慢性阻塞性肺疾病患者中选取符合纳入标准的患者108例,分为肺动脉压正常组（84例）与肺动脉压增高组（24例）,分析RDW以及Cys-C等指标。结果肺动脉压增高组RDW值[（15.19±1.69）%]明显较正常组[（14.38±1.42）%]高;肺动脉压增高组Cys-C值[（1.32±0.41）]明显较正常组[（0.95±0.46）]高,差异有统计学意义（P<0.01）。RDW、Cys-C与肺动脉高压均呈正相关,两者差异有统计学意义（P<0.01）。结论 RDW和Cys-C值在慢阻肺继发肺动脉高压患者体内有明显的增高,均与肺动脉高压严重程度呈正相关。两者对判断慢性阻塞性肺疾病继发肺动脉高压严重程度具有重要的临床价值。

关键词: 红细胞分布宽度, 胱抑素-C, 慢性阻塞性肺疾病, 相关性分析, 肺动脉高压

Abstract: Objective Effects of red blood cell distribution width,Cys-C secondary pulmonary hypertension in patients with chronic obstructive pulmonary disease and its severity of predictive value. Method From our hospital in 2012 during the April to June 2015 were selected in patients with chronic obstructive pulmonary disease into standard patient 108 cases,and divided into the normal pulmonary artery pressure group （84 cases） and the increased pulmonary artery pressure group （24 cases）. Observe the red blood cell distribution width （RDW） and Cys-C and other indicators are analyzed. Result The red blood cell distribution width （RDW） value in the increased pulmonary artery pressure group [（15.19±1.69） %] was significantly higher than in the normal group [（14.38±1.42）%] （P<0.01）; the Cys-C value in the increased pulmonary artery pressure group [（1.32±0.41）] was significantly higher than in the normal group [（0.95±0.46）] （P<0.01）. RDW,Cys-C and pulmonary hypertension were positive correlation and the difference were statistically significant （P<0.01）. Conclusion Red blood cell distribution width （RDW） and Cys-C values are secondary pulmonary hypertension in copd patients have obviously increased,are positively correlated with pulmonary hypertension severity. Red blood cell distribution width and Cys-C also to predict chronic obstructive pulmonary disease severity of secondary pulmonary hypertension has important clinical value,is a reliable predictor for the disorder.

Key words: Red blood cell distribution width, Cys-C, Chronic obstructive pulmonary disease, Correlation analysis, Pulmonary arterial hypertension

中图分类号:

R446.11R563

孙莹, 刘长春, 郝丽梅, 王佳, 王春玲. RDW、Cys-C与慢性阻塞性肺疾病患者继发肺动脉高压关系的研究[J]. 临床输血与检验, 2018, 20(5): 531-533.

SUN Ying, LIU Chang-chun, HAO Li-mei, etal. Red Blood Cell Distribution Width,Cys-C Secondary Pulmonary Hypertension in Patients with Chronic Obstructive Pulmonary Disease and its Severity of Predictive Value[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2018, 20(5): 531-533.

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RDW、Cys-C与慢性阻塞性肺疾病患者继发肺动脉高压关系的研究

Red Blood Cell Distribution Width,Cys-C Secondary Pulmonary Hypertension in Patients with Chronic Obstructive Pulmonary Disease and its Severity of Predictive Value

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