• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

临床输血与检验 ›› 2020, Vol. 22 ›› Issue (2): 215-217.DOI: 10.3969/j.issn.1671-2587.2020.02.025

• 临床检验 • 上一篇    下一篇

三种不同仪器检测超敏C反应蛋白结果的一致性分析

何广营, 林晓玲, 李冯坚   

  1. 518109 广东省深圳市龙华区人民医院检验科(何广营,李冯坚);
    深圳市龙华区中心医院检验科(林晓玲)
  • 收稿日期:2018-09-18 出版日期:2020-04-20 发布日期:2020-04-16
  • 作者简介:何广营(1985-),男,广东河源人,主管技师,学士,主要从事分子生物学和临床检验工作,(Tel) 13418692741( E-mail)he13418692741@163.com。

Consistency Analysis of Results of Hypersensitive C-reactive Protein Detected by Three Different Instruments

HE Guang-ying, LIN Xiao-ling, LI Feng-jian   

  1. Laboratory Department of Shenzhen Longhua District People's Hospital, Shenzhen,Guangdong 518109
  • Received:2018-09-18 Online:2020-04-20 Published:2020-04-16

摘要: 目的 比较3种不同仪器检测超敏C反应蛋白(hypersensitive C-reactive protein,hs-CRP)结果的一致性。方法 选择2018年3~7月来深圳龙华区人民医院门诊就诊的感染发烧患者156例,采用VITROS5600全自动干片生化免疫分析仪和AU5800生化分析仪检测血清中hs-CRP浓度,以及迈瑞BC5390血球-超敏一体机检测全血中hs-CRP。以参加卫生部室间质评的AU5800作为参考仪器,VITROS5600和5390作为对比仪器,分析3种不同仪器检测hs-CRP结果的一致性。结果 156例患者血清中hs-CRP浓度参考仪器检测结果为93.64±79.74 mg/L,迈瑞5390全自动血球-超敏C反应蛋白一体机检测结果为87.98±76.57 mg/L,两者之间差异无统计学意义(t=0.9124,P>0.05),而VITROS5600干片生化分析仪检测结果为182.38±158.79 mg/L,明显高于参考仪器,差异有统计学意义(t=6.805 6,P<0.05)。3种仪器检测hs-CRP浓度之间均呈正相关,5390与AU5800E和VITROS5600与AU5800之间相关系数(r2)分别为0.968 5和0.953 0。结论 5390血球-超敏C反应蛋白一体机和AU5800生化分析仪检测hs-CRP结果具有良好的一致性,而VITROS5600干片生化免疫分析仪检测的结果明显偏高,但3种不同仪器检测hs-CRP具有良好的正相关。

关键词: 强生VITROS5600, 贝克曼AU5800, 迈瑞BC-5390, 超敏C反应蛋白, 一致性

Abstract: Objective To compare the consistency of the results of hypersensitive c-reactive protein (hs-CRP) detected by three different instruments. Methods From march to July, 2018, 156 cases of patients with infection and fever who visited the outpatient department of Longhua district people's hospital in Shenzhen were selected. Using AU5800 as the reference instrument and VITROS5600 and 5390 as the comparison instruments, the consistency of hs-CRP test results of three different instruments was analyzed. Results In serum of 156 cases of hs-CRP reference instrument test results concentration was 93.64±79.74 mg/L, Mindray 5390 automatic blood corpuscle-hypersensitive c-reactive protein all-in-one test results was 87.98±76.57 mg/L, there was no statistically significant difference between the two (t=0.912 4, P>0.05), while VITROS5600 dry piece of biochemical analyzer test results was 182.38±158.79 mg/L, significantly higher than the reference instrument, the difference was statistically significant (t=6.805 6, P<0.05). The correlation coefficient (r) between hs-CRP concentration detected by the three instruments was 0.968 5. The correlation coefficient (r) between VITROS5600 and AU5800 was 0.953 0. Conclusion The results of hs-CRP detected by 5390 hemocyte-hypersensitive c-reactive protein integrator and AU5800 biochemical analyzer were consistent, while the results detected by VITROS5600 dry platebiochemical immune analyzer were obviously higher, but the hs-CRP detected by 3 different instruments showed good positive correlation.

Key words: Johnson & Johnson VITROS5600, Beckman AU5800, Mindray BC-5390, Hypersensitive c-reactive protein, Consistency

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