MicroRNAs与红系生长发育、增殖、分化及凋亡相关性研究进展

doi:10.3969/j.issn.1671-2587.2020.04.026

临床输血与检验 ›› 2020, Vol. 22 ›› Issue (4): 445-448.DOI: 10.3969/j.issn.1671-2587.2020.04.026

• 综述 • 上一篇

MicroRNAs与红系生长发育、增殖、分化及凋亡相关性研究进展

赵星云, 卞茂红

230022 安徽医科大学第一附属医院

收稿日期:2019-03-08 出版日期:2020-08-20 发布日期:2020-08-12
通讯作者: 卞茂红, 男, 教授, 硕士生导师, 主要从事miRNA与红系之间的相关性研究, （E-mail）mhbian@126.com。
作者简介:赵星云（1993-）, 女, 安徽马鞍山人, 在读硕士, 主要从事miRNA的相关性研究, （E-mail） 15856380312@163.com。

Advances in Research on Relationship between MicroRNAs and Erythroid Growth, Proliferation, Differentiation and Apoptosis

ZHAO Xing-yun, BIAN Mao-hong

The First Affiliated Hospital of Anhui Medical University, Anhui 230022

Received:2019-03-08 Online:2020-08-20 Published:2020-08-12

摘要/Abstract

摘要： MicroRNA（miRNA）是一种内源性的非编码单链小分子RNA, 它是通过与靶基因3'UTR区结合来调控靶基因的表达。miRNA在红细胞生命代谢过程中发挥重要作用, 本文意在对miRNA参与调节红系生长发育、增殖、分化及凋亡的机制进行综述。

关键词: 红细胞的生长发育, 增殖, 分化, 凋亡, MicroRNAs

Abstract: MicroRNA（miRNA） is endogenously small non-coding regulatory RNA which plays important roles in many critical processes. It regulates gene expression through binding to the untranslated region of target mRNA. MicroRNA acts as a vital part in erythropoiesis. In this review, we mean to summarize the state of knowledge on the role of miRNAs in the regulation of different stages of erythropoiesis.

Key words: Erythropoiesis, Proliferation, Differentiation, Apoptosis, MicroRNA

中图分类号:

R331.1⁺41

赵星云, 卞茂红. MicroRNAs与红系生长发育、增殖、分化及凋亡相关性研究进展[J]. 临床输血与检验, 2020, 22(4): 445-448.

ZHAO Xing-yun, BIAN Mao-hong. Advances in Research on Relationship between MicroRNAs and Erythroid Growth, Proliferation, Differentiation and Apoptosis[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2020, 22(4): 445-448.

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MicroRNAs与红系生长发育、增殖、分化及凋亡相关性研究进展

Advances in Research on Relationship between MicroRNAs and Erythroid Growth, Proliferation, Differentiation and Apoptosis

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