自体富血小板血浆治疗儿童病理性骨折疗效观察*

doi:10.3969/j.issn.1671-2587.2023.03.011

临床输血与检验 ›› 2023, Vol. 25 ›› Issue (3): 354-357.DOI: 10.3969/j.issn.1671-2587.2023.03.011

自体富血小板血浆治疗儿童病理性骨折疗效观察^*

刘琴, 沈先涛, 徐春芬, 王阳, 杨柳春, 胡红兵

430015 湖北武汉,华中科技大学同济医学院附属武汉儿童医院输血科（刘琴,徐春芬,王阳,杨柳春,胡红兵）; 华中科技大学同济医学院附属武汉儿童医院小儿骨科（沈先涛）

收稿日期:2023-05-06 发布日期:2023-07-10
通讯作者: 胡红兵,主任技师,主要从事临床输血与医学检验的研究,（E-mail）whfesx@163.com。
作者简介:刘琴,副主任技师,主要从事临床输血与医学检验的研究,（E-mail）liuqin20051224@aliyun.com。
基金资助:
^*本课题受湖北省卫生健康委联合基金输血专项-重点项目（No.WJ2019H339）资助

Efficacy of Autologous Platelet-rich Plasma in Pathologic Fracture Healing in Children

LIU Qin, SHEN Xiantao, XU Chunfen, et al

Wuhan Children's Hospital（Wuhan Maternal and Child Healthcare Hospital）,Tongji Medical College,Huazhong University of Science & Technology,Wuhan,Hubei 430015

Received:2023-05-06 Published:2023-07-10

摘要/Abstract

摘要： 目的观察与评价自体富血小板血浆（PRP）用于治疗儿童病理性骨折的疗效。方法对武汉儿童医院11例根据临床资料和影像学检查确诊为病理性骨折且需要骨科手术治疗的患儿进行研究,将接受手工制备方法制备自体PRP进行治疗的患儿采用作为治疗组,未接受自体PRP治疗作为对照组,随访观察患儿术后骨折愈合情况,并询问患者的满意度。结果接受PRP治疗的4名患儿均未发生不良反应,相对于对照组患儿骨折愈合周期较短（χ²=4.860,P=0.027）,患儿及其家属满意度较高（χ²=4.860,P=0.027）。结论 PRP治疗能促进儿童病理性骨折的愈合,缩短治疗周期,提升患者满意度。

关键词: 自体富血小板血浆, 病理性骨折, 儿童

Abstract: Objective To assess the efficacy of autologous platelet-rich plasma （aPRP） treatment in children with pathologic fractures. Methods Eleven children in Wuhan Children's Hospital who were diagnosed with pathologic fractures and required orthopedic surgery based on clinical data and imaging examination,were enrolled. Children treated with aPRP prepared by manual preparation method were selected as the treatment group,while those not treated with aPRP were selected as the control group. The postoperative fracture healing was observed and patient satisfaction was carried. Results No adverse reactions occurred in the 4 children treated with PRP, and the fracture healing cycle was shorter than that in the control group（χ²=4.860,P=0.027）. The satisfaction of the children and their families was higher（χ²=4.860,P=0.027）. Conclusion Platelet-rich plasma enhance pathologic fracture healing in children and shorten treatment time. It improves patient satisfaction.

Key words: Autologous platelet-rich plasma, Pathological fractures, Children

中图分类号:

R457

刘琴, 沈先涛, 徐春芬, 王阳, 杨柳春, 胡红兵. 自体富血小板血浆治疗儿童病理性骨折疗效观察^*[J]. 临床输血与检验, 2023, 25(3): 354-357.

LIU Qin, SHEN Xiantao, XU Chunfen, et al. Efficacy of Autologous Platelet-rich Plasma in Pathologic Fracture Healing in Children[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2023, 25(3): 354-357.

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自体富血小板血浆治疗儿童病理性骨折疗效观察^*

Efficacy of Autologous Platelet-rich Plasma in Pathologic Fracture Healing in Children

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