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临床输血与检验

临床输血与检验 ›› 2017, Vol. 19 ›› Issue (3): 281-283.DOI: 10.3969/j.issn.1671-2587.2017.03.020

• 血液检测 • 上一篇    下一篇

献血者HIV筛查结果的回顾性分析及灰区设置的探讨*

郭巍, 张婷   

  1. 100853 北京解放军总医院输血科
  • 收稿日期:2017-01-05 出版日期:2017-06-20 发布日期:2017-06-23
  • 通讯作者: 张婷,女,硕士,主要从事临床输血工作,（E-mail）zhangting810626@163.com。
  • 作者简介:郭巍（1987-）,女,河北保定人,检验师,学士,（E-mail）626673531@qq.com。
  • 基金资助:
    *本课题受解放军总医院扶持基金项目（No.2015FC-TSYS-1037） 资助

Retrospective Analysis of HIV Screening Results Among Blood Donors and the Establishment of Grey Area

GUO Wei, ZHANG Ting   

  1. Department of Blood Transfusion,Chinese PLA General Hospital,100853
  • Received:2017-01-05 Online:2017-06-20 Published:2017-06-23

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摘要： 目的 探讨ELISA法的HIV筛查实验灰区设置的必要性。方法 将2012~2016年献血者初筛有反应性的标本送HIV确证实验室进行确证,初筛结果按S/CO值区间分组进行回顾性分析。结果 2012~2016年共检测献血者标本165 189例,双试剂或单试剂双孔复查有反应性上报HIV确证实验室630例,其中确证阳性96例;索林试剂初筛有反应性标本514例,115例S/CO值位于0.8~1.0区间的确证结果均为阴性;金豪试剂初筛有反应性标本239例,17例S/CO值位于0.8~1.0区间的确证结果均为阴性。结论 ELISA法的HIV筛查实验没有必要设置灰区。

关键词: 人类免疫缺陷病毒, 回顾性分析, 灰区

Abstract: Objective To discuss the necessity of grey area in HIV screening experiment of ELISA. Methods The blood sample which was reactive in the preliminary screening from 2012 to 2016 were sent to the HIV confirmation laboratory. The Results of preliminary screening were analyzed retrospectively according to S/CO value. ResultFrom 2012 to 2016,165189 cases blood donors were detected. 630 cases were reported to HIV confirmation laboratory by double reagent reactive or single reagent was double reactivity. Positive Results were confirmed in 96 cases.514 cases were reactive in the reagent of Sorin. 115 cases of S/CO value in the 0.8-1.0 interval were negative. 239 cases were reactive in the reagent of Jinhao. 17 cases of S/CO value in the 0.8-1.0 interval were negative. Conclusion To set the grey area in the HIV screening test by ELISA is unnecessary.

Key words: HIV, Retrospective analysis, Grey area

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