Abstract: Objective To research the method of freeze-dried cryoprecipitate and evaluate its effect. Methods Forty units of fresh whole blood （200ml） were collected from volunteer donors. Two bags of cryoprecipitate with same capacity were prepared from each unit of whole blood by conventional method,one bag was stored at-20℃ as frozen cryoprecipitate,and the other was prepared into freeze-dried cryoprecipitate after adding Compound Amino Acid Injection by lyophilizer and stored at 4℃. Two sets of cryoprecipitates from 20 donors were taken out and analyzed for factor Ⅷ,fibrinogen,and pH after 24 h,and the other cryoprecipitates were evaluated after 12 months. Results There are no significant differences of factor Ⅷ,fibrinogen,and pH between frozen and freeze-dried cryoprecipitate after 24 hours,and 12 months storage,respectively （P>0.05）. Conclusion The freeze-dried cryoprecipitate stored at 4℃ after 12 months remain normal factor Ⅷ and fibrinogen contents and can be used as blood reserve for wartime.

Key words: Freeze-dried cryoprecipitate, Factor Ⅷ, Fibrinogen