Abstract: Objective To provide evidence for effective use of platelet through analyzing the efficiency of platelets transfusion and its influencing factors. Methods Statistical analysis was carried out for 276 times of platelet transfusion in 136 patients based on gender，age，blood groups，transfusion frequency，and splenomegaly. Peripheral blood PLT count and clinical symptoms of hemorrhage were evaluated for platelet transfusion efficiency. Results One hundred and ninety-four transfusions were found to be effective in 276 transfusions （70.29%）. Both sex and age showed no significant impact on platelet transfusion efficiency （P>0.05）. The frequency of platelet transfusion negatively correlated with transfusion efficiency （P<0.05）. The patients with splenomegaly presented a significant impact on platelet transfusion efficiency （P<0.01）. Conclusions The transfusion frequency and splenomegaly are influencing factors of the transfusion efficiency. Attention should be paid to the indications of the patients in PLT transfusion so as to reduce or avoid the occurrence of invalid transfusion and improve the efficiency of PLT transfusion and clinical efficacy.

Key words: Platelet transfusion, Platelet count , Transfusion efficiency