Abstract: Objective To know the changes of hemogram and coagulation index after blood transfusion in medical patients. To provide clinical evidence for improving the transfusion efficacy in medical patients. Methods 116 patients received blood transfusion were screened from December 1st，2016 to May 31st，2017. Blood indicators before and after transfusion were analyzed．116 patients were divided into continuous blood transfusion and discontinuous blood transfusion groups，then we computed the average changes of red blood cells（）and hemoglobin（）in 24 hours after blood transfusion respectively. SPSS 23.0 software was applied for statistical treatment. Results A total of 116 patients received transfusion．The median red blood cells was 2.23 units. Each unit blood could increase red blood cell 0.21×1012/L and hemoglobin 6.30 g/L. The basic diseases played no significant role in the effect of blood transfusion in 24 hours. Compared with the discontinuous blood transfusion and the first time of the continuous blood transfusion groups，there existed significant differences in the average changes of red blood cells and hemoglobin after second time of the continuous blood transfusion group（P<0.05）. Conclusion Medical patients were recommended to be transfused with blood continuously in 24 hours. The effect of blood transfusion would be improved obviously.

Key words: Hemoglobin , Blood transfusion continuously , Transfusion efficacy