Abstract: Objective To analyze the research of platelet transfusion cut-off value by meta-analysis in China. Methods Non-randomized concurrent control trials of different platelet transfusion thresholds published in China were searched and retrieved from Cnki.net,SinoMed,VIP and WANFANG DATA by November of 2016. Platelet transfusion threshold of 10×10⁹/L and 20×10⁹/L were designated to A group and B group,respectively. RevMan5. 3 software was applied to the meta-analysis for platelet transfusion effectiveness,bleeding incidence,times and doses of platelet transfusion and adverse reactions in patients of the two groups.Results Nine studies were selected for meta-analysis,covering a total of 1520 patients．Platelet transfusion efficiency was [RR=1.08,95%CI （1.00,1.18）,P= 0.06]; total bleeding incident rate was [RR=1.18,95%CI （0.95,1.47）,P=0.14]; platelet transfusion dose was [SMD=-0.79,95%CI（-1.59,0.02）,P=0.06]; frequency of platelet transfusion was [SMD=-1.21,95%CI （-2.12,-0.31）,P=0.009]; and the total adverse reaction rate was [RR=0.55,95%CI（0.38,0.79）,P=0.001]. Conclusion It is relatively safe for the patients with hematologic diseases,in stable conditions and with no obvious risk factors,to take 10×10⁹/L as a prophylactic platelet transfusion threshold.

Key words: Platelet transfusion, Threshold, Effective rate, Adverse reaction, Meta-analysis