• 中国科学论文统计源期刊
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JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2023, Vol. 25 ›› Issue (3): 383-387.DOI: 10.3969/j.issn.1671-2587.2023.03.017

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Effect and Clinical Significance of FFP Infusion on Hemagglutination Index of Newborn

Li Yiwen, YU-LAN Jingzi, TAO Yuqi, et al   

  1. Department of Blood Transfusion, The First Affiliated Hospital of Wannan Medical College, Wuhu 241000
  • Received:2023-03-14 Published:2023-07-10

Abstract: Objective To explore the effect of FFP infusion in neonates and its clinical significance, we compared the changes of coagulation convention parameters before and after fresh frozen plasma (FFP) infusion and. Methods A total of 55 patients in neonatal intensive care unit (NICU) of our hospital were selected to retrospectively analyze the changes of coagulation function indexes before and after FFP infusion and the correlation between them. Results All indexes of coagulation function were significantly improved after FFP infusion in neonates(P<0.05); There was no significant correlation between the increase or decrease of coagulation indexes after FFP infusion (before /after FFP infusion) and gestational age, body weight, APGAR score and infusion volume. Conclusion FFP infusion can cause the changes of hemagglutination index in neonates, significantly improve the clotting function of critically ill neonates, and contribute to the recovery of fibrinolytic system,to reduce the risk of thrombosis in children.

Key words: Plasma infusion, Newborn, Coagulation function, Fresh frozen plasma

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