Abstract: Objective To analyze the prevalence of HIV infection among Chinese college student blood donors, providing evidence for blood bank to formulate appropriate blood screening strategies for college students. Methods Relevant studies published were searched through databases including CNKI, Wanfang, PubMed, and Embase. Data were extracted and subjected to meta-analysis using R software. Results A total of 16 studies were eligible with a cumulative sample size of 914 193 donors and 93 HIV-positive cases. The pooled HIV prevalence among Chinese college student blood donors was 0.007% (95%CI: 0.005%~0.009%). Subgroup analysis revealed statistically significant differences by gender and sample size (P<0.05), but not by region, study period, or detection method (P>0.05). Conclusion The HIV positive rate among Chinese college student blood donors has maintained stable low, with a significantly higher prevalence in males than in females. The potential residual risk of transfusion-transmitted HIV cannot be overlooked.

Key words: College students, Blood donors, HIV, Meta-analysis