Abstract: Ojective To prepare recruitment and detection strategies for blood donationsand to ensure the safety of blood transfusion.Methods A total of 434700 blood donors were selectedin Zhongshan area from 2006 to 2015.HIV positive blood donors were grouped according to gender,age,frequency and blood components of donations in comply with the confirmatory tests of the CDC of Zhongshan city.Results Fifty two HIV cases were found in 434700 blood donors,with an incidence of 11.96/104.Among them males were 15.19/104（82.69%）and females were 5.93/104.Young adults,the middle aged and elderly accounted for 9.05/104（53.85%）,19.36/104,and 3.93/104,respectively.Prevalence of HIV infection was found to be 18.34/104（80.77%）,12.22/104,and 23.29/104（11.54%） in the first time,repeated and fixed donors,respectively.All HIV cases （12.56/104） were found in whole blood donations;55.77% of them （10.57/104） came from group blood donations; and 14.37/104 were found to be street blood donators.Conclusions HIV infection in blood donators is a critical issue in Zhongshan area.High technology with sensitivity,reliability and viral sterilization must be used for blood donor screening to ensure the safety of transfusion.

Key words: HIV, Blood donors, Influence