• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2021, Vol. 23 ›› Issue (2): 152-155.DOI: 10.3969/j.issn.1671-2587.2021.02.004

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Investigation of CD36 Antigen Deficiency in Unpaid Blood Donors in Hefei

ZHAO Na-na, WANG Chao, JIN Hui-xin, et al   

  1. Anhui Blood Center, Hefei 230031
  • Received:2020-09-23 Online:2021-04-20 Published:2021-04-19

Abstract: Objective To investigate the frequency of CD36 antigen deficiency in blood donors in Hefei. Methods A total of 973 blood samples of healthy platelet donors were randomly collected in Hefei blood center from March 2020 to July 2020. Flow cytometry was used for CD36 antigen detection. Platelet-rich plasma was prepared for detection CD36 antigen on platelets, and the residual cells were treated with erythrocyte lysate for CD36 antigen on monocytes. Results Among 973 platelet donors,16 donors were found platelet CD36 antigen deficiency, of which 2 were type I CD36 deficiency,14 were type II CD36 deficiency with the frequency 0.21% and 1.44% respectively. Conclusion The blood donors population in Hefei has certain CD36 antigen deficiency.

Key words: Blood donors, Platelets, CD36 antigen, Flow cytometry

CLC Number: