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临床输血与检验

临床输血与检验 ›› 2016, Vol. 18 ›› Issue (5): 459-461.DOI: 10.3969/j.issn.1671-2587.2016.05.017

• 临床输血研究 • 上一篇    下一篇

血小板形态MPV PDW值的差异对单采血小板收集量的影响与对策

陆庆屯   

  1. 223800 江苏省宿迁市中心血站
  • 收稿日期:2016-02-16 出版日期:2016-10-20 发布日期:2017-05-19
  • 作者简介:陆庆屯（1958-）,男,江苏灌云人,副主任医师,学士,主要从事采供血管理和血液病临床诊疗工作,(Tel)0527-84385815（E-mail)lqtlqt808@163.com。

Influence of Platelet Morphology Reference Values on the Harvest of Single Donor Platelets

LU Qing-tun   

  1. Suqian Blood Bank of Jiangsu Province,Suqian 223800
  • Received:2016-02-16 Online:2016-10-20 Published:2017-05-19

PDF

568

被引次数

3

摘要： 目的 探讨献血前与产品的血小板形态参数的差异,分析其影响因素,寻找改进措施,保障单采血小板的含量符合要求。方法 统计2007~2014年经质检血小板含量<2.5×1011/袋24例,≥2.5×1011/袋344例。按血小板含量2.5×1011/袋为分界线分成2组,研究组间献血前MPV、PDW与产品的MPV、PDW是否存在差异。结果 血小板采集量≥2.5×1011/袋组与<2.5×1010/袋组的献血前MPV、PDW组间差异具有统计学意义,而2组产品的MPV、PDW之间的差异不具有统计学意义。结论 献血前血小板形态变异,影响血小板采集量。对于献血前MPV>9.085 5 fl或 PDW>12.5756%的献血者考虑采集效率降低,应适当增加处理全血量或暂缓献血。

关键词: 血小板形态, 参考值, 单采血小板

Abstract: Objective To investigate the variation of the platelet morphology parameters before blood donation and its impact on the production of the single donor platelet. Methods According to the quality inspection result ,24 cases of platelet collections from January 2007 to December 2014 produced less than 2.5 ×1010/ bag, and 344 cases over 2.5 ×1011/ bag. These samples were divided into two groups according to the separatrix of 2.5×1011/ bag and analyzed for the difference between the two groups of MPV and PDW before blood donation and the platelet production. Results The difference between the two groups in MPV and PDW over or below 2.5×1011/bag was statistically significant before blood donation; while no obvious difference was noted between MPV and PDW in the same group. Conclusion Blood platelet morphology variation before blood donation affects platelet production of collection. The plateletcollection efficiency may decrease in the blood donor with MPV>9.085 5 fl or PDW > 12.575 6% before blood donation, an appropriate large volum of whole blood might be collected, or the blood donation should be postponed.

Key words: Platelet morphology, Reference value, Single donor platelets

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