中药调节血小板凝血功能的研究进展*

doi:10.3969/j.issn.1671-2587.2025.01.020

临床输血与检验 ›› 2025, Vol. 27 ›› Issue (1): 140-144.DOI: 10.3969/j.issn.1671-2587.2025.01.020

• 综述 • 上一篇

中药调节血小板凝血功能的研究进展^*

钟诚, 骆展鹏

重庆市血液中心,重庆 400052

收稿日期:2024-08-26 发布日期:2025-02-25
通讯作者: 骆展鹏,主要从事血站质量管理、血液成分制备、免疫遗传研究,（E-mail）19741644@qq.com。
作者简介:钟诚,主要从事血小板输注研究,（E-mail）1093665772@qq.com。
基金资助:
*本课题受重庆市九龙坡区科技计划项目（No.2023-03-020-Y）资助

Research Progress on the Regulation of Platelet Coagulation Function by Traditional Chinese Medicine

ZHONG Cheng, LUO zhanpeng

Chongqing Blood Center, Chongqing 400052

Received:2024-08-26 Published:2025-02-25

摘要/Abstract

摘要： 血小板在血液凝聚和血栓形成中扮演着重要角色,其功能异常可能导致血栓性疾病的发生。中药作为传统医学的重要组成部分,自古以来被广泛运用于调节血液功能。本文综述了近年来关于中药对血小板凝血功能影响的研究。首先讨论了中药对血小板粘附和血管壁亲和力、调节血小板聚集和释放功能中的作用,包括对ADP介导的血小板聚集和钙离子内流的调节等;其次概述了中药用于治疗血小板功能异常相关疾病的研究现状;最后展望了中药与现代医学结合的未来发展方向,强调了中药在血栓性疾病治疗中的潜力和进一步研究的必要性。

关键词: 中药, 血小板功能, 血栓

Abstract: Platelets play an important role in blood aggregation and thrombosis, and their abnormal function may lead to thrombotic diseases. Traditional Chinese medicine (TCM), as an important component of traditional medicine, has been widely used since ancient times to regulate blood function. This paper reviews the recent studies on the effects of TCM on platelet coagulation function. Firstly, the effects of TCM on platelet adhesion, vascular wall affinity, platelet aggregation and release were discussed, including the regulation of ADP-mediated platelet aggregation and calcium influx. Secondly, the research status of some TCM used in the treatment of diseases related to platelet dysfunction was summarized. Finally, the future development direction of the combination of TCM and modern medicine was discussed, emphasizing the potential of TCM in the treatment of thrombotic diseases and the necessity of further research.

Key words: Traditional Chinese medicine, Platelet function, Thrombus

中图分类号:

R457R28

钟诚, 骆展鹏. 中药调节血小板凝血功能的研究进展^*[J]. 临床输血与检验, 2025, 27(1): 140-144.

ZHONG Cheng, LUO zhanpeng. Research Progress on the Regulation of Platelet Coagulation Function by Traditional Chinese Medicine[J]. JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE, 2025, 27(1): 140-144.

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中药调节血小板凝血功能的研究进展^*

Research Progress on the Regulation of Platelet Coagulation Function by Traditional Chinese Medicine

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