• 中国科学论文统计源期刊
  • 中国科技核心期刊
  • 美国化学文摘(CA)来源期刊
  • 日本科学技术振兴机构数据库(JST)

临床输血与检验 ›› 2017, Vol. 19 ›› Issue (6): 628-630.DOI: 10.3969/j.issn.1671-2587.2017.06.029

• 血型与临床 • 上一篇    下一篇

孕妇中RhE抗原阴性分布特点*

杨劲, 何安华, 李凌波   

  1. 230001 安徽省合肥市第二人民医院输血科(杨劲,何安华);
    长春博迅生物技术有限责任公司(李凌波)
  • 收稿日期:2017-06-12 出版日期:2017-12-20 发布日期:2017-12-13
  • 通讯作者: 何安华,女,副主任检验师,(Tel)13856074033。
  • 作者简介:杨劲(1981-),男,安徽固镇人,回族,主管技师,学士,主要从事输血医学工作,(E-mail)16571243@qq.com。
  • 基金资助:
    *本课题受吉林省科技厅重点科技成果转化项目(No.20150307011YY)资助

The Positive RhE Antigen Frequency in Pregnant Women

YANG Jin, HE An-hua, and LI Ling-bo   

  1. Department of Blood Transfusion, the Second Hospital of Hefei?230001
  • Received:2017-06-12 Online:2017-12-20 Published:2017-12-13

摘要: 目的 探讨 RhE抗原阴性孕妇妊娠和生产次数与抗-E产生的关系。方法 采用微柱凝胶法对2 012例孕妇进行RhE抗原、不规则抗体和ABO血型检测,并对不规则抗体阳性的孕妇进行谱细胞鉴定,检测抗-E。结果 孕妇中RhE抗原阴性占53%;抗-E在首次妊娠与未育妊娠次数1次以上孕妇中的差异无统计学意义(P>0.05);抗-E在首次妊娠与生育1次以上孕妇中的差异有统计学意义(P<0.05);RhE抗原阴阳性孕妇在ABO血型分布的差异无统计学意义(P>0.05)。结论 RhE阴性孕妇占比超过50%,抗-E产生以生育1次以上孕妇为主,在日益增多的生二胎家庭中意义重大。

关键词: RhE, 妊娠, 经产妇

Abstract: Objective To explore the relations between times of delivery and anti-E antibody frequencies in RhE- negative pregnancies. Methods Micro-column gel test was used to detect RhE antigens, irregular antibodies and ABO blood groups in 2012 pregnant women, and spectral cell identification was performed to detect anti-E antibodies in the samples with positive irregular antibodies. Results Fifty percent pregnant women were found to be RhE antigen-negative. No significant difference of positive rates of anti-E antibodies was noted between the women with first pregnancy and those with over one time of pregnancy(P>0.05). Additionally, no obvious difference of ABO blood group distribution was seen between RhE-negative and –positive pragnancies (P>0.05). Conclusions Over half of pregnant women present negative RhE antigen and the positive anti-E antibodies are frequently detectable in multipara women, which is significantly meaningful to the women with a second child.

Key words: RhE, Pregnancy, Multipara

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