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JOURNAL OF CLINICAL TRANSFUSION AND LABORATORY MEDICINE ›› 2024, Vol. 26 ›› Issue (6): 721-725.DOI: 10.3969/j.issn.1671-2587.2024.06.001

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Strengthening the Application of Centrifugal Technology and Establishing a Combined Apheresis/Blood Purification System in the Department of Transfusion Medicine

ZHUANG Yuan, YU Yang   

  1. Department of Blood Transfusion, First Medical Center of Chinese PLA General Hospital, Beijing 100853
  • Received:2024-07-08 Online:2024-12-20 Published:2024-12-20

Abstract: Non-transfusional hemotherapy should be mainly carried out by the Transfusion Department, which basis is the apheresis technology by centrifugation. The plasmapheresis can be realized in two ways: centrifugal and membrane filtration, each of which has its own technical characteristics. Apheresis/blood purification based on centrifugation shows the advantages of higher plasma separation efficiency, shorter treatment time, less platelet loss, less destruction of red blood cells, and the use of citrate anticoagulation for non-continuous clinical treatment of critically ill patients. Secondary columns suitable for centrifugal technology can realize immunoadsorption, artificial liver support system, centrifugation-filtration plasmapheresis and inflammatory factor adsorption. Using increasingly sophisticated secondary column technology should be a useful supplement to traditional TPE.

Key words: Non-transfusional hemotherapy, Immunoadsorption, Artificial liver support system, Centrifugation-filtration plasmapheresis

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