Abstract: ObjectiveBy screening the Mur antigen and anti-Mur among the blood donors of Panyu district of Guangzhou, analyzing the frequencies and distribution characteristics of Mur blood group in the area. MethodBy using monoclonal anti-Mur reagent and 96-well micro plate method, Mur antigen of blood donors were screened. By using Mur antigen positive red blood cells reagent, anti-Mur of plasma samples were screened, the screened positive samples were carried out antibody specific identification. ResultsIn 3 000 samples of blood donors, 215 cases of Mur antigen positive samples were detected, the frequency was 7.17%. In 15 000 samples of blood donors 30 cases of anti-Mur were screened and identified, the frequency was 0.20%. ConclusionThere is a relatively high frequency of Mur antigen distribution as well as the frequency of anti-Mur in blood donors in the region. It’s necessary to increase red blood cells containing Mur antigen in the preparation of irregular antibody screening reagent cells to prevent anti -Mur antibody undetected, and furtherly reduce the risk of adverse clinical plasma transfusion reaction.

Key words: Mur, antigen, Blood, donor, Frequency, distribution