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临床输血与检验

临床输血与检验 ›› 2017, Vol. 19 ›› Issue (3): 240-242.DOI: 10.3969/j.issn.1671-2587.2017.03.009

• 临床输血 • 上一篇    下一篇

血栓弹力图在儿童免疫性血小板减少症治疗中的应用

张笑盼, 宋继军, 马曙轩   

  1. 450000 河南省郑州儿童医院输血科（张笑盼,宋继军）;
    北京儿童医院输血科（马曙轩）
  • 收稿日期:2016-12-23 出版日期:2017-06-20 发布日期:2017-06-23
  • 通讯作者: 宋继军,男,副主任技师,主要从事临床输血研究,（Tel）15003998000（E-mail）songjj1970@163.com。
  • 作者简介:张笑盼（1988-）,女,河南商丘人,学士,检验师,主要从事临床输血研究,（Tel）13523439172。

The Application of Blood Thrombelastograph in the Treatment of Children Immune Thrombocytopenia

ZHANG Xiao-pan, SONG Ji-jun, MA Shu-xuan   

  1. Childerens Hospital of Zheng Childerens Hospital of Zheng zhou 45000
  • Received:2016-12-23 Online:2017-06-20 Published:2017-06-23

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摘要： 目的 探讨血栓弹力图（TEG）在儿童免疫性血小板减少症治疗中的应用价值。方法 对北京儿童医院146例儿童免疫性血小板减少症（ITP）患者的TEG检测结果进行分析,以血小板数量（PLT）为依据分为3组：治疗组、观察组和缓解组。结果 3组R、K、Angle、MA的差异均有统计学意义（P<0.01）,其中治疗组的MA、Angle明显低于参考值。两两比较组间MA、Angle的差异有统计学意义（P<0.01）。治疗组与观察组R的差异无统计学意义（P>0.05）,缓解组与其他两组R的差异均有统计学意义（P<0.01）;治疗组与观察组K的差异无统计学意义（P>0.017）,缓解组与其他两组K的差异均有统计学意义（P<0.017）。结论 血栓弹力图对儿童免疫性血小板减少症的治疗具有指导意义。

关键词: 血栓弹力图, 免疫性血小板减少症, 血小板功能

Abstract: Objective To explore the clinical significance of thrombelastogragh（TEG） in children immune thrombocytopenia （ITP）. Methods The levels of blood TEG in 146 patients with ITP from the Beijing children's hospital were analyzed,and the Results were analyzed statistically. The cases were divided into three groups including therapy group,observation group and alleviate group according to the PLT levels. Results There were statistical differences among the three groups of R、K、Angle and MA（P<0.01）,while the treatment group was obviously lower than the reference value in MA and Angle,and difference exists in any two group in MA and Angle（P<0.01）. Although there was no difference between therapy group and observation group in R（P>0.05） and K（P>0.017）,there were differences between alleviate group and the others group in R（P<0.01） and K（P<0.017）. Conclusions TEG is important for the treatment of children immune thrombocytopenia。

Key words: Thrombelastograph, Immune thrombocytopenia, Platelet function

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