冷藏血小板输注后的清除机制*

doi:10.3969/j.issn.1671-2587.2022.02.023

临床输血与检验 ›› 2022, Vol. 24 ›› Issue (2): 249-252.DOI: 10.3969/j.issn.1671-2587.2022.02.023

冷藏血小板输注后的清除机制^*

王璐, 姚春艳

400038 陆军军医大学第一附属医院输血科

收稿日期:2021-10-21 发布日期:2022-04-12
通讯作者: 姚春艳,女,副教授,博士生导师,主要从事血液安全与临床输血研究,（E-mail）yaochunyan@tmmu.edu.cn。
作者简介:王璐（1998-）,女,学士,主要从事医学检验技术方面研究,（E-mail）772079051@qq.com。
基金资助:
*本课题受重庆市自然科学基金面上项目（No.cstc2021jcyj-msxm3693）资助

Received:2021-10-21 Published:2022-04-12

摘要/Abstract

摘要： 血小板输注可用于预防和治疗血小板数量减少或功能异常所导致的出血,目前临床上普遍采用（22±2）℃振摇对血小板进行保存。研究发现4℃冷藏后的血小板用于治疗急性出血患者效果良好,但冷藏血小板输注后易被机体快速清除,在体内的循环时间明显缩短。为延长血小板输注后的循环时间,对冷藏血小板输注后的清除机制进行研究显得尤为重要。本综述就目前冷藏血小板输注后的清除机制进行总结。

关键词: 冷藏血小板, 去唾液酸化, GPIbα, 血管性血友病因子

中图分类号:

R331.1⁺43

王璐, 姚春艳. 冷藏血小板输注后的清除机制^*[J]. 临床输血与检验, 2022, 24(2): 249-252.

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冷藏血小板输注后的清除机制^*

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