关键词: 大容量, 输液, 输血, 加温加压

Abstract: Objective To investigate the core performance of the self-developed heating and pressurizing blood transfusion apparatus （transfusion speed/temperature controllable）. Methods We compared the flow rate between normal saline（NS）and suspended red blood cells（sRBCs）at room temperature by using the IBP Medical,detected the output temperatures of NS（initial temperatures of（10±0.5）℃ and（20±0.5）℃）under the heating conditions of 36℃,38℃,40℃ and 42℃ and flow rates of 50 mL/min,100 mL/min,150 mL/min and 200 mL/min by a digital thermometer. We also detected the output temperature of sRBCs refrigerated at 2~6℃ under the heating condition of 42℃ and the flow rate of 50 mL/min,100 mL/min,150 mL/min and 200 mL/min,and compare the differences before and after heating and pressurizing of free hemoglobin （FHb）,potassium ion concentration and blood routine.Results There was no significant difference between the actual flow rate of NS and sRBCs（P>0.05）. The output temperature of NS with initial temperature of（10±0.5）℃ and（20±0.5）℃ could reach 31~34 ℃ by heating and pressurizing blood transfusion apparatus. Under the conditions of different flow rates at 42℃, the output temperatures of refrigerated sRBCs at 4 ℃ were（40.8±0.3）℃,（36.4±0.2）℃,（34.7±0.9）℃and（32.8±0.4）℃,which were higher than the initial temperature（P<0.05）. After heating and pressurization, the FHb content in the supernatant of sRBCs increased significantly（P<0.05）,but still met the national standard（≤0.72 g/L）; There was no statistical difference in potassium ion concentration,HGB,HCT,MCV and MCH indexes before and after heating and pressurization.Conclusion The apparatus showed a good heating and pressurizing effect and little influence on hemolysis of sRBCs.

Key words: High volume, Infusion, Blood transfusion, Heat and pressurization