Abstract: ObjectiveBy the retrospective analysis of Rh （D） negative patients with special circumstances of emergency rescue transfusion application of "matching blood transfusion" case data,to explore the application of the safety and effectiveness of combined transfusion. MethodCompared the effectiveness of 6 matched blood transfusion（case group） and 6 with same type blood transfusion （control group）in Xinjiang' aksu area from January 2014 to December 2015,to explore matched blood transfusion's safety and effectiveness. The effectiveness indexes include patients basic information,red cell antibody screening,total bilirubin（TBIL）,concentration of hemoglobin（Hb）,reticulocyte count（Ret）,hematocrit（Hct）and hospitalization days. ResultsThe patients in cases group and control group after blood transfusion 72 h red cell antibody screening was negative and did not produce anti-D,Hb after blood transfusion 24 h was actually appreciated in 28.53±10.09 g/L and 21.24±3.13 g/L,there was no significant difference compared with the experimental data of control group and case group by T text. ConclusionThe matched blood transfusion of Rh（D）-negative matched blood transfusion with special circumstances of emergency rescue transfusion have the same effectiveness and safety,at the same time,the matched blood transfusion of the Rh（D）positive red blood cells of patients should also be established to standardize the trace,follow-up and evaluation system.

Key words: Rh（D）, negative, Special, circumstances, Emergency, rescue, Matched, blood, transfusion