Abstract: Venous thromboembolism (VTE) is a common vascular diso with complex and diverse etiologies, often presenting with atypical symptoms. The primary manifestations include deep vein thrombosis in the lower extremities and pulmonary thromboembolism. Early diagnosis and timely treatment are crucial for improving the prognosis of VTE. The border defense personnel in Xinjiang, stationed at high altitudes, experience a higher incidence of VTE. Due to limited access to first-line medical resources, clinical misdiagnosis or delayed diagnosis is common. The combined use of D-dimer testing and imaging techniques plays a vital role in the accurate diagnosis and evaluation of VTE. Additionally, potential biomarkers such as von Willebrand factor and soluble P-selectin hold promise for early and rapid diagnosis, monitoring high-risk populations, and assessing the effectiveness of anticoagulant and thrombolytic therapies.

Key words: Venous Thromboembolism, Diagnosis, Biomarkers, SP-selectin, Von Willebrand factor